Sequential Embryo Transfer


In this method, healthy and developed embryos are transferred twice to the patient’s womb, on day 2/3 and day 5/6, whichever is deemed fit by your embryologist.
This is done to ensure that embryos that got great quality grading during selection get chances of being implanted inside a womb under natural conditions.


What Is The Normal Process Of Fertilization During ASequential Embryo Transfer- IVF Cycle?

Sequential Embryo Transfer may be better, or many patients for many reasons since all embryos communicate with the parent uterus using various hormones called cytokines.

These cytokines help the uterus prepare itself for implantation. Most patients have a different kind of fluid makeup inside the oviduct and generally, most patients have a dissimilar uterus.

It is the embryo that tells the uterus what it needs for development and implantation.

It has been noted that the presence of a group of embryos on Day 3 sometimes helps with the implantation of a second group of embryos and lead to possible pregnancy since the uterus was properly prepared during the second implantation.


Is Sequential Embryo TransferFor Me?

Not all patients develop embryos via IVF that can survive up to the blastocyst stage. If your older IVF treatments failed owing to no reason or you are over the age of 35, this procedure might work best for you.

In case your developed embryos exhibit arrested development after the first few days of fertilization, you should opt for this procedure since some women develop arrested embryos no matter what laboratory conditions are kept by the embryologist for your embryos. This can be due to genetic defects or other issues in your body.

Since the normal window of implantation for any human embryo is between 7 to 10 days after ovulation has completed, the 10th day exhibits the fall of the endometrial lining if the embryo does not implant itself.

To counter this, another set of embryos are placed inside the uterus to help them develop onto the blastocyst stage since only those can implant successfully into the uterus.


How Does The Sequential Embryo TransferProcedure Work?


Sequential embryo transfer is a more improved method of increasing chances of your pregnancy and successful embryo implantation in infertile couples.

Patients who undergo Sequential embryo transfer have a marvellous pregnancy rate of over 50% since sequential transferaims to transfer two groups of embryos within the same menstrual cycle of an infertile woman undergoing IVF treatment for infertility.

One group of embryos (the fastest growing embryos are transferred to the uterus 2 or 3 days after the oocytes (human eggs) are collected from the ovary).

The second group of embryos(more highly developed) are transferred into the uterus just a few days later, when at least one of those embryos has hopefully reached the expanded blastocyst stage.

This is done only to increase your chances of getting pregnant in case your older IVF treatments failed.


Risk Factors


Sequential embryo transfernormally has an increased implantation rate since a larger number of embryos for implanting are set inside the uterus.

Due to this, the chances of multiple births are greatly increased and can lead you to delivering more than one baby.

Is Sequential Embryo TransferA Safe Procedure For Her?


  • This procedure is extremely safe and embryo transfer is done twice in the same cycle.
  • Sequential embryo transfer decreases the need for cryopreserving the extra embryos that may not turn out be survivors in the long run since they will mostly be implanted into the uterus to see their success rate.
  • The blastocysts that were not transferred can still be cryopreserved. They can be thawed later for a frozen embryo transfer (FET) during another try at IVF.


Who Can I Talk To If I Have Further Questions?

When you opt for a Sequential Embryo Transferprocedure cycle, your Physician will explain to you all the details about the procedure and the possible risks involved with it.

  • The medical staff at our IVF centre is highly familiar with the procedure and can give you all the latest information regarding it.
  • We encourage you to ask as many questions as you can to be assured that all your queries have been answered.