SET-Single Embryo Transfer

SET is known as Single Embryo Transfer, an IVF process by which a good quality blastocyst embryo is transferred back to the patient’s womb for a possible pregnancy.
The embryos that successfully survive to the blastocyst stage of future zygote development are more likely to be stronger and healthier.
Since its inception in the year 2002, the number of patients opting for SET (Single Embryo Transfers) has increased. Nearly 20% of all IVF patients and 41% of donor egg patients have successfully elected to transfer a single embryo which has resulted in an astounding 61% clinical pregnancy rate for IVF and close to 62% pregnancy rate for a donor egg.

What Is The Normal Process Of Fertilization During A SET – IVF Cycle?


The blastocyst normally possesses an Inner-cell mass (ICM) which forms the embryo in the future. The outer layer of a blastocyst consists of many cells that are called the trophoblast which protects inner cell mass and the fluid-filled cavity called the blastocele. The trophoblast is what develops into the placenta in the future.

Blastocyst embryos (day 5) have a higher chance of successfully implanting into the womb as compared to a 4 cell (day 2), or 8 cell (day 3) embryos since they are more developed and attach to the womb quickly.

This method is also cost-effective since fewer embryos are needed to achieve a successful pregnancy.

 Is SET For Me?


SET is a perfect option for people opting for IVF and who want to avoid the risk of encountering a twin pregnancy. You can opt for SET if you:

  • are under the age of 37.
  • are currently undergoing your 1st or 2nd IVF treatment cycle. Please make sure that you did not have failed IVF attempts in the past.
  • are able to successfully produce at least 4 good quality embryos on day 3 of your egg retrieval. This can be determined only based on your previous IVF treatment records or based on your embryo development during the current cycle.

Please note that SET is not suitable for all kinds of recipients, so always discuss your options with your IVF expert before opting for this procedure.

How Does The SETProcedure Work?


  • Factors which can affect your chances of a successful pregnancy via SET can include embryo quality, endometriosis, tubal disease (fallopian tube) or whether you could get pregnant with IVF before or not.
  • Single-embryo transfer (SET) is a procedure in which one single embryo is selected from a larger number of available healthy embryos and is then placed inside the uterus or fallopian tube via a catheter.
  • The selected embryo can belong to a previous IVF cycle (cryopreserved embryos) or from the current IVF cycle so that more than one embryos are available for scrutiny. The remaining healthy embryos are restored back to cryopreservation for future use.


Risk Factors


  • SET eliminates the chances of multiple births that come with the risk of premature birth and very low birth-weight in infants.
  • Compared to a double embryo transfer, there could be a 5% lower chance of pregnancy but it also drastically reduces the obstetric complications and risk to baby or mother due to risk of multiple pregnancy.

Is SETA Safe Procedure For Her?


  • SET is much safer compared to other IVF treatments since it eliminates the risk of multiple pregnancies.
  • SET gives you one of the best possible chances of birthing a healthy baby.
  • Since not everyone’s embryos reach the day 5 blastocyst stage, you are a better chance of pregnancy than others. Sometimes a day 3 transfer can be done if your IVF specialist deems it fit.

Who Can I Talk To If I Have Further Questions?

When you opt for an IVF cycle, your Physician will explain to you all the details about the procedure and its possible risks involved with it.

The medical staff at our IVF center is highly familiar with the procedure and can give you all the latest information regarding it.

We encourage you to ask as many questions as you can to be assured that all your queries have been answered.